A relatively new family of medications known as biologic response modifiers has shown significant promise in decreasing the symptoms and slowing the progress of rheumatoid arthritis. These drugs directly modify the immune system by inhibiting proteins called cytokines, which contribute to inflammation. Examples of these are etanercept, infliximab, adalimumab and anakinra. Recent research has shown that some of these drugs may cause an increased risk of cancer, especially in children and teenagers. Talk with your healthcare provider about the risks and benefits of these medications.