If you have sweating all over your body, your doctor may prescribe an anticholinergic drug. Anticholinergics work by blocking the actions of acetylcholine. Acetylcholine is a chemical in your body that helps stimulate your sweat glands, making them produce more sweat. Signs and symptoms generally improve in about two weeks. But because acetylcholine is involved in many areas of your body, it can have various negative side effects.